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Non-Surgical treatments generally are quite effective in most patients with Androgenic alopecia and suffice requirements of most of the men and women.
In majority of patients, these treatment lead to a substantial hair growth, much more than what can be transferred with Hair Transplant. Hence, it is preferable to explore these treatments before considering surgery like Hair Transplant.
These treatments work the best to

    Reduce the hair loss
    Improve thickness of hair
    Improve volume of hair
    Improve density of hair in the areas where there is thinning of hair
    In early cases of Androgenic alopecia
    In advanced cases of Androgenic alopecia ( since Hair transplant is not suitable for larger requirement of hair follicles )

Hair Transplant is best suited to treat localized hair loss due to Androgenic alopecia. Hence it is good to advance hair line or correct temporal recession in patients who have normal thick hair (no thinning of hair) on rest of the scalp.
Hair Transplant should be chosen with caution in patients with generalized thinning of hair with active hair loss.

Medical Treatments
The following drugs have been approved by the FDA for the treatment of androgenetic alopecia:

    Minoxidil: Androgen-independent hair-growth stimulator
    Finasteride: 5-Alpha reductase type 2 inhibitor

Mesotherpay involves injecting certain neutraceuticals into the scalp. They provide vital nourishment to hair follicles and reduce hair loss. They also improve growth of existing hair. However, these injections are not very effective in achieving new hair growth. Hence the volume of existing hair improves but not the density.
These injections are usually repeated at weekly intervals for about 3 to 8weeeks

Platelet Rich Plasma – Stem Cell treatment
PRP-Stem Cell treatmentis the latest in the treatments aimed at achieving hair regeneration.
Patients with the following expectations make good candidates for PRP-Stem Cell Therapy

    Reduce the hair loss
    Reduce the further graying of hair (already white hair cannot turn black again)
    Improve thickness of hair
    Improve volume of hair
    Improve density of hair in the areas where there is thinning of hair
    Early cases of Androgenic alopecia
    Advanced cases of Androgenic alopecia (since Hair transplant is not suitable for larger requirement of hair follicles)
    Patients who wish to avoid surgery

The procedure involves drawing out about 10ml of one’s own blood (similar to what is collected in a pathology laboratory for normal blood tests). This blood is processed to separate platelet and stem cell rich plasma. This plasma rich in platelets and growth factors is very useful in tissue regeneration and healing.  It is then injected in the scalp or rubbed on the scalp after performing a dermaroller treatment in the areas which suffer from thinning of hair. Injection technique is far superior to dermaroller technique because valuable stem cells and platelets are not wasted due to surface drying.
In some patients just one treatment may be sufficient. However, more than one treatment at 2 weeks interval may be considered for more pronounced improvement.
New hair growth is observed within a 4-6 weeks. The result can be objectively analyzed and documented using dermacopic examination of scalp and serial photographs.
Numerous studies have documented how PRP-Stem Cell treatment works. The injection of PRP activates follicular progenitor cells (adult stem cells). PRP is loaded with growth factors that promote rapid angiogenesis and localized cell growth. PRP causes miniaturized hair follicles to become healthier and larger, producing more robust hair growth. It shortens the latent Telogen phase and prolongs the anagen phase. Effective for both male and female pattern hair loss, PRP has also regrown hair even in alopecia aerata and eyebrow hypotrichosis.

Surgical treatment of androgenetic alopecia has been successfully performed for the past 4 decades. Although the cosmetic results are often satisfactory, the main problem is covering the bald area with donor plugs (or follicles) sufficient in number to be effective. Micrografting produces a more natural appearance than the old technique of transplanting plugs.



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